产品货号：
Z10963
中文名称：
ANTXR1抗体
英文名称：
Anti-ANTXR1 Antibody
产品规格：
0.1mg
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-ANTXR1 Antibody |
| 指标别名 | anthrax toxin receptor 1;ANTXR1;ATR;TEM8;Tumor endothelial marker 8 |
| 克隆性 | Polyclonal |
| 检验物种 | human,mouse,rat |
| 应用范围 | ELISA,WB,IHC,IF |
| 基因名称 | ANTXR1 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | ATR antibody was raised against a peptide corresponding to 13 amino acids near the center of human ATR.The immunogen is located within amino acids 220 - 270 of ATR. |
| 计算分子量 | 63kDa |
| 成分 | ATR Antibody is supplied in PBS containing 0.02% sodium azide. |
| 纯化方式 | ATR Antibody is Ion exchange chromatography purified. |
| 浓度 | 1mg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 4℃可保存3个月，-20℃可保存1年。 |
| 背景资料 | The Anthrax toxin receptor (ATR) was initially discovered as the tumor endothelial marker 8 (TEM8).This protein,which exists in three isoforms (36,40,and 60kDa),is highly expressed in tumor vessels as well as in the vasculature of developing embryos,suggesting that it may normally play a role in angiogenesis.However,it also acts as the receptor for anthrax toxin.Following the binding of this protein by the protective antigen (PA) of anthrax,PA is cleaved and heptamerizes to form the binding site for both edema factor (EF) and lethal factor (LF).This complex is then endocytosed by the cell;acidification in endosomes allows the release of EF and LF into the cytoplasm where they interfere with MAPK signaling and induce apoptosis. |
| Uniprot ID | Q9H6X2 |
| 基因名全称 | Anthrax toxin receptor 1 |
| 蛋白名全称 | Anthrax toxin receptor 1 |
| 推荐稀释比 | ATR antibody can be used for detection of ATR by Western blot at 0.5 to 2μg/mL.Antibody can also be used for immunohistochemistry starting at 2μg/mL.For immunofluorescence start at 10μg/mL.Antibody validated:Western Blot in human samples;Immunohistochemistry in human samples and Immunofluorescence in human samples.All other applications and species not yet tested. |
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